Comparative Safety, Immunogenicity, and Efficacy of CEF Cell-Based and DF-1 Cell Line Adapted Infectious Bursal Disease Vaccines in Specific-Pathogen-Free Chickens

Infectious bursal disease (IBD) is an immunosuppressive and economically important disease of young chickens caused by infectious bursal disease virus (IBDV). The National Veterinary Institute (Bishoftu, Ethiopia) produces intermediate IBDV vaccine using primary chicken embryo fibroblast (CEF) cells...

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Bibliographic Details
Main Authors: Daniel Workineh, Molalegne Bitew, Daniel Oluwayelu, Belayneh Getachew, Takele Abayneh, Esayas Gelaye, Hawa Mohammed, Tedros Fikru, Mastewal Birhan, Bereket Dessalegn, Getaw Deresse, Kassaye Adamu, Saddam Mohammed Ibrahim
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2022/5392033