Harmine enhances the activity of the HIV-1 latency-reversing agents ingenol A and SAHA
Infection with human immunodeficiency virus 1 (HIV-1) remains incurable because long-lived, latently-infected cells persist during prolonged antiretroviral therapy. Attempts to pharmacologically reactivate and purge the latent reservoir with latency reactivating agents (LRAs) such as protein kinase...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2020-12-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/9/12/bio052969 |