Small open reading frames: a comparative genetics approach to validation

Small open reading frames: a comparative genetics approach to validation

Abstract Open reading frames (ORFs) with fewer than 100 codons are generally not annotated in genomes, although bona fide genes of that size are known. Newer biochemical studies have suggested that thousands of small protein-coding ORFs (smORFs) may exist in the human genome, but the true number and...

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Bibliographic Details
Main Authors: Niyati Jain, Felix Richter, Ivan Adzhubei, Andrew J. Sharp, Bruce D. Gelb
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Genomics
Subjects:
Micropeptides
Small open reading frames
Human genetic variation
Evolutionary conservation
Comparative genetics
Online Access:https://doi.org/10.1186/s12864-023-09311-7

Internet

https://doi.org/10.1186/s12864-023-09311-7

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