Early CAR− CD4+ T‐lymphocytes recovery following CAR‐T cell infusion: A worse outcome in diffuse large B cell lymphoma

Early CAR− CD4+ T‐lymphocytes recovery following CAR‐T cell infusion: A worse outcome in diffuse large B cell lymphoma

Abstract CAR− CD4+ T cell lymphopenia is an emerging issue following CAR‐T cell therapy. We analyzed the determinants of CD4+ T cell recovery and a possible association with survival in 31 consecutive patients treated with commercial CAR‐T for diffuse large B‐cell (DLBCL) or mantle cell lymphoma. Ci...

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Bibliographic Details
Main Authors: Massimiliano Gambella, Simona Carlomagno, Rosa Mangerini, Nicoletta Colombo, Alessia Parodi, Chiara Ghiggi, Livia Giannoni, Elisa Coviello, Chiara Setti, Silvia Luchetti, Alberto Serio, Antonella Laudisi, Monica Passannante, Alessandra Bo, Elisabetta Tedone, Simona Sivori, Emanuele Angelucci, Anna Maria Raiola
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:eJHaem
Subjects:
cell therapy
immunophenotype
non‐Hodgkin lymphoma
Online Access:https://doi.org/10.1002/jha2.871

Internet

https://doi.org/10.1002/jha2.871

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