Pharmacokinetic assessment of isoniazid and acetylisoniazid in carbon tetrachloride-induced liver injury model in Wistar rats

Pharmacokinetic assessment of isoniazid and acetylisoniazid in carbon tetrachloride-induced liver injury model in Wistar rats

Background: N-acetyl transferase 2 (NAT2) polymorphism testing could not see the light of success as a biomarker tool in tuberculosis management. Additionally, the antitubercular treatment (ATT) drug's reintroduction regimen variations exist because of the scarcity of robust preclinical evidenc...

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Bibliographic Details
Main Authors: Swati Sharma, Aishwarya Anand, Nipun Verma, Vishal Sharma, Alka Bhatia, Amol N Patil, Dibyajyoti Banerjee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
acetylisoniazid
carbon tetrachloride
drug-induced liver injury
isoniazid
pharmacokinetics
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=3;spage=139;epage=145;aulast=Sharma

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http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=3;spage=139;epage=145;aulast=Sharma

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