Noncapped Genomic RNA Are Critical for Alphaviral Infection and Pathogenicity

Alphaviruses are positive-sense RNA arthropod-borne viruses that represent a significant threat to public health. During alphaviral replication, significant quantities of viral genomic RNAs that lack a canonical 5’ cap structure are produced and packaged into viral particles, despite the fact that t...

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Bibliographic Details
Main Authors: Autumn T. LaPointe, Kevin J Sokoloski
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/50/1/44