Noncapped Genomic RNA Are Critical for Alphaviral Infection and Pathogenicity
Alphaviruses are positive-sense RNA arthropod-borne viruses that represent a significant threat to public health. During alphaviral replication, significant quantities of viral genomic RNAs that lack a canonical 5’ cap structure are produced and packaged into viral particles, despite the fact that t...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
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Series: | Proceedings |
Subjects: | |
Online Access: | https://www.mdpi.com/2504-3900/50/1/44 |