TisB Protein Protects Escherichia coli Cells Suffering Massive DNA Damage from Environmental Toxic Compounds

ABSTRACT Toxin-antitoxin systems are genetic elements that are widespread in prokaryotes. Although molecular mode of action of many of these toxins has been identified, their biological functions are mostly unknown. We investigated the functional integration of the TisB/IstR toxin-antitoxin system i...

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Bibliographic Details
Main Authors: Wei-Lin Su, Marie-Florence Bredèche, Sara Dion, Julie Dauverd, Bénédicte Condamine, Arnaud Gutierrez, Erick Denamur, Ivan Matic
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.00385-22