Homodimerized cytoplasmic domain of PD-L1 regulates its complex glycosylation in living cells
Membrane-anchored PD-L1 homodimerizes in cells. N-glycosylation of PD-L1 regulates its homodimerization. The formation of PD-L1 homodimers further regulates their glycan processing, localization to the plasma membrane, and binding to PD-1.
Bibliographic Details
| Main Authors: |
Li Zhou,
Fangni Chai,
Yong He,
Zhihui Zhou,
Shupan Guo,
Pan Li,
Qi Sun,
Xueyin Zu,
Xin Liu,
Qin Huang,
Yanping Zhong,
Aolan Zhou,
Xueyun Wang,
Haiyan Ren |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-08-01
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| Series: | Communications Biology
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| Online Access: | https://doi.org/10.1038/s42003-022-03845-4
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