Inhibition of autophagosome-lysosome fusion contributes to TDCIPP-induced Aβ1-42 production in N2a-APPswe cells

Inhibition of autophagosome-lysosome fusion contributes to TDCIPP-induced Aβ1-42 production in N2a-APPswe cells

Alzheimer's disease is the most common form of dementia and is characterized by cognitive impairment. The disruption of autophagosome-lysosome function has been linked to the pathogenesis of Alzheimer's disease. Tris (1,3-dichloro-2-propyl) phosphate (TDCIPP) is a widely used organophospho...

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Bibliographic Details
Main Authors: Chunli Zou, Tingting Yang, Xinfeng Huang, Xiaohu Ren, Chen Yang, Benhong Xu, Jianjun Liu
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Alzheimer's disease
TDCIPP
Autophagy
Aβ42
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024028639

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024028639

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