Basic and applied uses of genome‐scale metabolic network reconstructions of Escherichia coli
Abstract The genome‐scale model (GEM) of metabolism in the bacterium Escherichia coli K‐12 has been in development for over a decade and is now in wide use. GEM‐enabled studies of E. coli have been primarily focused on six applications: (1) metabolic engineering, (2) model‐driven discovery, (3) pred...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2013-04-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2013.18 |