Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes

ABSTRACT Pathogenic mycobacteria contain up to five type VII secretion (T7S) systems, ESX-1 to ESX-5. One of the conserved T7S components is the serine protease mycosin (MycP). Strikingly, whereas MycP is essential for secretion, the protease activity of MycP1 in Mycobacterium tuberculosis has been...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Vincent J. C. van Winden, Roy Ummels, Sander R. Piersma, Connie R. Jiménez, Konstantin V. Korotkov, Wilbert Bitter, Edith N. G. Houben
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: American Society for Microbiology 2016-11-01
Cyfres:mBio
Mynediad Ar-lein:https://journals.asm.org/doi/10.1128/mBio.01471-16