In vivo imaging reveals impaired connectivity across cortical and subcortical networks in a mouse model of DYT1 dystonia

In vivo imaging reveals impaired connectivity across cortical and subcortical networks in a mouse model of DYT1 dystonia

Developing in vivo functional and structural neuroimaging assays in Dyt1 ΔGAG heterozygous knock-in (Dyt1 KI) mice provide insight into the pathophysiology underlying DYT1 dystonia. In the current study, we examined in vivo functional connectivity of large-scale cortical and subcortical networks in...

Full description

Bibliographic Details
Main Authors: Jesse C. DeSimone, Marcelo Febo, Priyank Shukla, Edward Ofori, Luis M. Colon-Perez, Yuqing Li, David E. Vaillancourt
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Neurobiology of Disease
Subjects:
Diffusion MRI
DYT1 dystonia
Free-water
Functional connectivity
Functional MRI
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116301632

Internet

http://www.sciencedirect.com/science/article/pii/S0969996116301632

Similar Items