Antitumoral Effect of Plocabulin in High Grade Serous Ovarian Carcinoma Cell Line Models

Antitumoral Effect of Plocabulin in High Grade Serous Ovarian Carcinoma Cell Line Models

Ovarian cancer (OC) is a life-threatening tumor and the deadliest among gynecological cancers in developed countries. First line treatment with a carboplatin/paclitaxel regime is initially effective in the majority of patients, but most advanced OC will recur and develop drug resistance. Therefore,...

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Bibliographic Details
Main Authors: Victoria Heredia-Soto, Javier Escudero, María Miguel, Patricia Ruiz, Alejandro Gallego, Alberto Berjón, Alicia Hernández, Marta Martínez-Díez, Shuyu Zheng, Jing Tang, David Hardisson, Jaime Feliu, Andrés Redondo, Marta Mendiola
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
plocabulin (PM060184)
microtubule inhibitor
high-grade serous ovarian cancer (HGSOC)
3D cell culture
drug testing
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.862321/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.862321/full

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