Brain Innate Immune Response in Diet-Induced Obesity as a Paradigm for Metabolic Influence on Inflammatory Signaling

Brain Innate Immune Response in Diet-Induced Obesity as a Paradigm for Metabolic Influence on Inflammatory Signaling

Obesity is a predisposing factor for numerous morbidities, including those affecting the central nervous system. Hypothalamic inflammation is a hallmark of obesity and is believed to participate in the onset and progression of the obese phenotype, by promoting changes in neuronal functions involved...

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Bibliographic Details
Main Authors: Felipe Macedo, Lucas Souza dos Santos, Isaias Glezer, Fernanda Marques da Cunha
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neuroscience
Subjects:
hypothalamus
inflammation
metabolism
microglia
obesity
saturated fatty acids
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00342/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.00342/full

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