NF-κB signaling in neoplastic transition from epithelial to mesenchymal phenotype

NF-κB signaling in neoplastic transition from epithelial to mesenchymal phenotype

Abstract NF-κB transcription factors are critical regulators of innate and adaptive immunity and major mediators of inflammatory signaling. The NF-κB signaling is dysregulated in a significant number of cancers and drives malignant transformation through maintenance of constitutive pro-survival sign...

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Bibliographic Details
Main Authors: Amy Oh, Makayla Pardo, Anaelena Rodriguez, Connie Yu, Lisa Nguyen, Olin Liang, Anna Chorzalska, Patrycja M. Dubielecka
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Communication and Signaling
Subjects:
NF-κB signaling
Chronic inflammation
Cell–cell junctions
Cytoskeletal reorganization
Apical-basolateral polarity
Epithelial-to-mesenchymal transition
Online Access:https://doi.org/10.1186/s12964-023-01207-z

Internet

https://doi.org/10.1186/s12964-023-01207-z

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