Therapeutic Role of Synthetic Lethality in ARID1A-Deficient Malignancies
AT-rich interaction domain 1A (ARID1A), a mammalian switch/sucrose nonfermenting complex subunit, modulates several cellular processes by regulating chromatin accessibility. It is encoded by ARID1A, an immunosuppressive gene frequently disrupted in a many tumors, affecting the proliferation, migrati...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Innovative Healthcare Institute
2024-02-01
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| Series: | Journal of Immunotherapy and Precision Oncology |
| Subjects: | |
| Online Access: | https://jipo.org/doi/pdf/10.36401/JIPO-22-37 |