Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells

Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells

Interactions between lymphoma cells and stromal cells play a key role in promoting tumor survival and development of drug resistance. We identified differences in key signaling pathways between the JeKo-1 and REC-1 mantle cell lymphoma (MCL) cell lines, displaying different patterns of stromal cell...

Full description

Bibliographic Details
Main Authors: Laia Sadeghi, Gustav Arvidsson, Magali Merrien, Agata M. Wasik, André Görgens, C.I. Edvard Smith, Birgitta Sander, Anthony P. Wright
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
B-cell receptor signaling
mantle cell lymphoma
ibrutinib
acalabrutinib
CXCR4
RNA sequencing
Online Access:https://www.mdpi.com/2072-6694/12/5/1143

Internet

https://www.mdpi.com/2072-6694/12/5/1143

Similar Items