Prenatal stress induces a depressive-like phenotype in adolescent rats: The key role of TGF-β1 pathway

Prenatal stress induces a depressive-like phenotype in adolescent rats: The key role of TGF-β1 pathway

Stressful experiences early in life, especially in the prenatal period, can increase the risk to develop depression during adolescence. However, there may be important qualitative and quantitative differences in outcome of prenatal stress (PNS), where some individuals exposed to PNS are vulnerable a...

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Bibliographic Details
Main Authors: Annamaria Fidilio, Margherita Grasso, Giuseppe Caruso, Nicolò Musso, Veronica Begni, Anna Privitera, Sebastiano Alfio Torrisi, Patrizia Campolongo, Stefania Schiavone, Fabio Tascedda, Gian Marco Leggio, Filippo Drago, Marco Andrea Riva, Filippo Caraci
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
depression
memory
TGF-β1
oxidative stress
prenatal stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1075746/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1075746/full

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