Combination PD-1 blockade and irradiation of brain metastasis induces an effective abscopal effect in melanoma

Nearly half of melanoma patients develop brain metastases during the course of their disease. Despite advances in both localized radiation and systemic immunotherapy, brain metastases remain difficult to treat, with most patients surviving less than 5 months from the time of diagnosis. While both tr...

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Bibliographic Details
Main Authors: Lukas W. Pfannenstiel, Corey McNeilly, Chaomei Xiang, Kai Kang, Claudia Marcella Diaz-Montero, Jennifer S. Yu, Brian R. Gastman
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1507669