Exploring the Potential of High-Molar-Activity Samarium-153 for Targeted Radionuclide Therapy with [<sup>153</sup>Sm]Sm-DOTA-TATE

Exploring the Potential of High-Molar-Activity Samarium-153 for Targeted Radionuclide Therapy with [<sup>153</sup>Sm]Sm-DOTA-TATE

Samarium-153 is a promising theranostic radionuclide, but low molar activities (A<sub>m</sub>) resulting from its current production route render it unsuitable for targeted radionuclide therapy (TRNT). Recent efforts combining neutron activation of <sup>152</sup>Sm in the SCK...

Full description

Bibliographic Details
Main Authors: Koen Vermeulen, Michiel Van de Voorde, Charlotte Segers, Amelie Coolkens, Sunay Rodriguez Pérez, Noami Daems, Charlotte Duchemin, Melissa Crabbé, Tomas Opsomer, Clarita Saldarriaga Vargas, Reinhard Heinke, Laura Lambert, Cyril Bernerd, Andrew R. Burgoyne, Thomas Elias Cocolios, Thierry Stora, Maarten Ooms
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
targeted radionuclide therapy
samarium-153
DOTA-TATE
SSTR<sub>2</sub>
Online Access:https://www.mdpi.com/1999-4923/14/12/2566

Internet

https://www.mdpi.com/1999-4923/14/12/2566

Similar Items