LncRNA HOTAIR down-expression inhibits the invasion and tumorigenicity of epithelial ovarian cancer cells by suppressing TGF-β1 and ZEB1

LncRNA HOTAIR down-expression inhibits the invasion and tumorigenicity of epithelial ovarian cancer cells by suppressing TGF-β1 and ZEB1

Abstract Background Epithelial ovarian cancer (EOC) is a pathological type with a higher mortality rate among gynecological cancers today. Long-chain noncoding RNAs (lncRNAs) can regulate the transcription and expression of cellular genes. However, the downstream molecules regulated by lncRNA HOTAIR...

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Bibliographic Details
Main Authors: Yufu Zhou, Yunjie Zhang, Yidan Shao, Xiaoli Yue, Yifan Chu, Cuiping Yang, Dengyu Chen
Format: Article
Language:English
Published: Springer 2023-12-01
Series:Discover Oncology
Subjects:
Epithelial ovarian cancer
lncRNA HOTAIR
Tumorigenicity
TGF-β1
ZEB1
Online Access:https://doi.org/10.1007/s12672-023-00846-5

Internet

https://doi.org/10.1007/s12672-023-00846-5

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