Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel <em>via</em> targeting miR-200b-3p/Bcl-2 axis

Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel <em>via</em> targeting miR-200b-3p/Bcl-2 axis

Development of docetaxel (TXT) resistance is a major obstacle for triple-negative breast cancer (TNBC) treatment. Additionally, chemoresistant cell-derived exosomes were able to change the chemo-response of chemosensitive recipient cells via transportation of lncRNAs. It has been shown that lncRNA...

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Bibliographic Details
Main Authors: Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li
Format: Article
Language:English
Published: PAGEPress Publications 2022-10-01
Series:European Journal of Histochemistry
Subjects:
Breast cancer
docetaxel
chemosensitivity
exosomes
long non-coding RNAs
Online Access:https://www.ejh.it/index.php/ejh/article/view/3529

Internet

https://www.ejh.it/index.php/ejh/article/view/3529

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