Understanding communication signals during mycobacterial latency through predicted genome-wide protein interactions and boolean modeling.

About 90% of the people infected with Mycobacterium tuberculosis carry latent bacteria that are believed to get activated upon immune suppression. One of the fundamental challenges in the control of tuberculosis is therefore to understand molecular mechanisms involved in the onset of latency and/or...

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Bibliographic Details
Main Authors: Shubhada R Hegde, Hannah Rajasingh, Chandrani Das, Sharmila S Mande, Shekhar C Mande
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3309013?pdf=render