The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype
Chromosomal translocations involving the nucleoporin <i>NUP98</i> gene are recurrently identified in leukemia; yet, the cellular defects accompanying NUP98 fusion proteins are poorly characterized. NUP98 fusions cause changes in nuclear and nuclear envelope (NE) organization, in particul...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-10-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/11/2851 |