The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype

Chromosomal translocations involving the nucleoporin <i>NUP98</i> gene are recurrently identified in leukemia; yet, the cellular defects accompanying NUP98 fusion proteins are poorly characterized. NUP98 fusions cause changes in nuclear and nuclear envelope (NE) organization, in particul...

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Bibliographic Details
Main Authors: Marcela Vaz, Birthe Fahrenkrog
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/11/2851