N-Arylacetamide derivatives of methyl 1,2-benzothiazine-3-carboxylate as potential drug candidates for urease inhibition

N-Arylacetamide derivatives of methyl 1,2-benzothiazine-3-carboxylate as potential drug candidates for urease inhibition

Urease enzyme is an infectious factor that provokes the growth and colonization of virulence pathogenic bacteria in humans. To overcome the deleterious effects of bacterial infections, inhibition of urease enzyme is one of the promising approaches. The current study is designed to synthesize new 1,2...

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Bibliographic Details
Main Authors: Sajila Hina, Sumera Zaib, Maliha Uroos, Muhammad Zia-ur-Rehman, Rubina Munir, Huma Riaz, Quratulain Syed, Syed Hussain Imam Abidi
Format: Article
Language:English
Published: The Royal Society 2023-04-01
Series:Royal Society Open Science
Subjects:
benzothiazine
synthesis
urease
thiourea
docking
ureolytic
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.230104

Internet

https://royalsocietypublishing.org/doi/10.1098/rsos.230104

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