Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes

Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes

Summary: Understanding the human antibody response to emerging viral pathogens is key to epidemic preparedness. As the size of the B cell response to a pathogenic-virus-protective antigen is poorly defined, we perform deep paired heavy- and light-chain sequencing in Ebola virus glycoprotein (EBOV-GP...

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Bibliographic Details
Main Authors: Elaine C. Chen, Pavlo Gilchuk, Seth J. Zost, Philipp A. Ilinykh, Elad Binshtein, Kai Huang, Luke Myers, Stefano Bonissone, Samuel Day, Chandrahaas R. Kona, Andrew Trivette, Joseph X. Reidy, Rachel E. Sutton, Christopher Gainza, Summer Diaz, Jazmean K. Williams, Christopher N. Selverian, Edgar Davidson, Erica Ollmann Saphire, Benjamin J. Doranz, Natalie Castellana, Alexander Bukreyev, Robert H. Carnahan, James E. Crowe, Jr.
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723003819

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http://www.sciencedirect.com/science/article/pii/S2211124723003819

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