A 12-mer Peptide of Tag7 (PGLYRP1) Forms a Cytotoxic Complex with Hsp70 and Inhibits TNF-Alpha Induced Cell Death

A 12-mer Peptide of Tag7 (PGLYRP1) Forms a Cytotoxic Complex with Hsp70 and Inhibits TNF-Alpha Induced Cell Death

Investigation of interactions between a pro-inflammatory cytokine tumor necrosis factor (TNFα) and its receptor is required for the development of new treatments for autoimmune diseases associated with the adverse effects of TNFα. Earlier, we demonstrated that the innate immunity p...

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Bibliographic Details
Main Authors: Elena A. Romanova, Tatiana N. Sharapova, Georgii B. Telegin, Alexei N. Minakov, Alexander S. Chernov, Olga K. Ivanova, Maxim L. Bychkov, Lidia P. Sashchenko, Denis V. Yashin
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
hsp70
tag7
tnfr1
apoptosis
necroptosis
rheumatoid arthritis
peptides
Online Access:https://www.mdpi.com/2073-4409/9/2/488

Internet

https://www.mdpi.com/2073-4409/9/2/488

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