Evidence for Increased Expression of SIRT3 Associated with Hyperandrogenism in Granulosa Cells of Non-Obese PCOS Patients

Evidence for Increased Expression of SIRT3 Associated with Hyperandrogenism in Granulosa Cells of Non-Obese PCOS Patients

Background: SIRT3 regulates the generation of reactive oxygen species (ROS) in human granulosa cells (GCs). Increased levels of oxidative stress may cause follicular dysplasia in GCs of polycystic ovary syndrome (PCOS) patients. However, expression and regulation of SIRT3 in GCs of PCOS patients hav...

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Bibliographic Details
Main Authors: Shen Zhang, Wenli Deng, Qiongyou Liu, Wei Yang
Format: Article
Language:English
Published: IMR Press 2022-11-01
Series:Clinical and Experimental Obstetrics & Gynecology
Subjects:
sirt3
polycystic ovary syndrome
luteinized granulosa cells
hyperandrogenism
oxidative stress
Online Access:https://www.imrpress.com/journal/CEOG/49/11/10.31083/j.ceog4911256

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https://www.imrpress.com/journal/CEOG/49/11/10.31083/j.ceog4911256

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