Evidence for Increased Expression of SIRT3 Associated with Hyperandrogenism in Granulosa Cells of Non-Obese PCOS Patients
Background: SIRT3 regulates the generation of reactive oxygen species (ROS) in human granulosa cells (GCs). Increased levels of oxidative stress may cause follicular dysplasia in GCs of polycystic ovary syndrome (PCOS) patients. However, expression and regulation of SIRT3 in GCs of PCOS patients hav...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
IMR Press
2022-11-01
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Series: | Clinical and Experimental Obstetrics & Gynecology |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/CEOG/49/11/10.31083/j.ceog4911256 |