Long non-coding RNA-NONMMMUT004552.2 regulates the unloading-induced bone loss through the miRNA-15b-5p/Syne1 in mice

Long non-coding RNA-NONMMMUT004552.2 regulates the unloading-induced bone loss through the miRNA-15b-5p/Syne1 in mice

Abstract Exercise-induced mechanical loading can increase bone strength whilst mechanical unloading enhances bone-loss. Here, we investigated the role of lncRNA NONMMUT004552.2 in unloading-induced bone-loss. Knockout of lncRNA NONMMUT004552.2 in hindlimb-unloaded mice caused an increase in the bone...

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Bibliographic Details
Main Authors: Zheng Zhang, Yu Jing, Ang Zhang, JiShan Liu, Heming Yang, Xiaotong Lou, Liyan Xu, Min Liu, Yikun Zhang, Jianwen Gu
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:npj Microgravity
Online Access:https://doi.org/10.1038/s41526-024-00382-8

Internet

https://doi.org/10.1038/s41526-024-00382-8

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