Effects of cordycepin on the microglia-overactivation-induced impairments of growth and development of hippocampal cultured neurons.

Microglial cells are normally activated in response to brain injury or immunological stimuli to protect central nervous system (CNS). However, over-activation of microglia conversely amplifies the inflammatory effects and mediates cellular degeneration, leading to the death of neurons. Recently, cor...

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Bibliographic Details
Main Authors: Jie Peng, Ping Wang, Hongshan Ge, Xianqin Qu, Xingliang Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416906?pdf=render