Amplification of HER2 is a marker for global genomic instability
<p>Abstract</p> <p>Background</p> <p>Genomic alterations of the proto-oncogene c-erbB-2 (HER-2/neu) are associated with aggressive behavior and poor prognosis in patients with breast cancer. The variable clinical outcomes seen in patients with similar HER2 status, given...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-10-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/8/297 |