Early vs. Delayed Initiation of Treatment With P2Y12 Inhibitors in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Early vs. Delayed Initiation of Treatment With P2Y12 Inhibitors in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

AimsWhether early or delayed dual antiplatelet therapy initiation is better in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is unclear. We assessed the evidence for comparing the efficacy and safety of early vs. delayed P2Y12 inhibitor initiation in NSTE-ACS.MethodsThe r...

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Bibliographic Details
Main Authors: Lourdes Vicent, Carlos Diaz-Arocutipa, Giuseppe Tarantini, Marco Mojoli, Adrian V. Hernandez, Héctor Bueno
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
clopidogrel
prasugrel
ticagrelor
P2Y12 inhibitors
Non-ST-segment elevation acute coronary syndrome
network meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.862452/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.862452/full

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