An unbiased proteomics approach to identify the senescence-associated secretory phenotype of human bone marrow-derived mesenchymal stem cells

Mesenchymal stem cells (MSCs) derived from bone marrow can support skeletal tissue repair and regeneration owing to their self-renewing capacity, differentiation ability, and trophic functions. Bone marrow-derived MSCs undergo dramatic changes with aging, including the senescence-associated secretor...

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Bibliographic Details
Main Authors: Rebekah M. Samsonraj, Susan F. Law, Abhishek Chandra, Robert J. Pignolo
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187223000220