Transmigration across a Steady-State Blood–Brain Barrier Induces Activation of Circulating Dendritic Cells Partly Mediated by Actin Cytoskeletal Reorganization

The central nervous system (CNS) is considered to be an immunologically unique site, in large part given its extensive protection by the blood–brain barrier (BBB). As our knowledge of the complex interaction between the peripheral immune system and the CNS expands, the mechanisms of immune privilege...

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Bibliographic Details
Main Authors: Megha Meena, Mats Van Delen, Maxime De Laere, Ann Sterkens, Coloma Costas Romero, Zwi Berneman, Nathalie Cools
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/11/9/700