Dental pulp stem cell-derived exosomes suppress M1 macrophage polarization through the ROS-MAPK-NFκB P65 signaling pathway after spinal cord injury

Dental pulp stem cell-derived exosomes suppress M1 macrophage polarization through the ROS-MAPK-NFκB P65 signaling pathway after spinal cord injury

Abstract Stem cell-derived exosomes have recently been regarded as potential drugs for treating spinal cord injury (SCI) by reducing reactive oxygen species (ROS) and suppressing M1 macrophage polarization. However, the roles of ROS and exosomes in the process of M1 macrophage polarization are not k...

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Bibliographic Details
Main Authors: Chao Liu, Fanqi Hu, Genlong Jiao, Yue Guo, Pan Zhou, Yuning Zhang, Zhen Zhang, Jing Yi, Yonggang You, Zhizhong Li, Hua Wang, Xuesong Zhang
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Journal of Nanobiotechnology
Online Access:https://doi.org/10.1186/s12951-022-01273-4

Internet

https://doi.org/10.1186/s12951-022-01273-4

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