Tenascin-C: Friend or Foe in Lung Aging?

Tenascin-C: Friend or Foe in Lung Aging?

Lung aging is characterized by lung function impairment, ECM remodeling and airspace enlargement. Tenascin-C (TNC) is a large extracellular matrix (ECM) protein with paracrine and autocrine regulatory functions on cell migration, proliferation and differentiation. This matricellular protein is highl...

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Bibliographic Details
Main Authors: Sandrine Gremlich, Tiziana P. Cremona, Eveline Yao, Farah Chabenet, Kleanthis Fytianos, Matthias Roth-Kleiner, Johannes C. Schittny
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Physiology
Subjects:
lung
extracellular matrix
Tenascin-C
aging
tenascin-C deficiency
lung physiology
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.749776/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.749776/full

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