Ectopic USP15 expression inhibits HIV-1 transcription involving changes in YY1 deubiquitination and stability

Ectopic USP15 expression inhibits HIV-1 transcription involving changes in YY1 deubiquitination and stability

IntroductionProtein homeostasis is maintained by the opposing action of ubiquitin ligase and deubiquitinase, two important components of the ubiquitin-proteasome pathway, and contributes to both normal physiological and pathophysiological processes. The current study aims to delineate the roles of u...

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Bibliographic Details
Main Authors: Sahar Rezaei, Khalid A. Timani, Ying Liu, Johnny J. He
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
USP15
ubiquitin variant inhibitors
deubiquitination
HIV-1 transcription
transcription factors
YY1 protein stability
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1371655/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2024.1371655/full

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