Profiling Microglia in a Mouse Model of Machado–Joseph Disease

Profiling Microglia in a Mouse Model of Machado–Joseph Disease

Microglia have been increasingly implicated in neurodegenerative diseases (NDs), and specific disease associated microglia (DAM) profiles have been defined for several of these NDs. Yet, the microglial profile in Machado–Joseph disease (MJD) remains unexplored. Here, we characterized the profile of...

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Bibliographic Details
Main Authors: Ana Bela Campos, Sara Duarte-Silva, Bruno Fernandes, Sofia Pereira das Neves, Fernanda Marques, Andreia Teixeira-Castro, Andreia Neves-Carvalho, Daniela Monteiro-Fernandes, Camila Cabral Portugal, Renato Socodato, Teresa Summavielle, António Francisco Ambrósio, João Bettencourt Relvas, Patrícia Maciel
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomedicines
Subjects:
microglia
Machado–Joseph disease
cell morphology
RNA-sequencing
machine learning
Online Access:https://www.mdpi.com/2227-9059/10/2/237

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https://www.mdpi.com/2227-9059/10/2/237

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