Play-the-winner rule and adaptive designs of clinical trials

In another paper, we have argued that the traditional randomized design of clinical trials is ethically infeasible in desperate medical situations and adaptive designs are morally required. We have also argued that in such situations, the appropriate designs must satisfy what we call the Principle o...

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书目详细资料
Main Authors: Xikui Wang, Daryl Pullman
格式: 文件
语言:English
出版: Hindawi Limited 2001-01-01
丛编:International Journal of Mathematics and Mathematical Sciences
在线阅读:http://dx.doi.org/10.1155/S0161171201005750