Medium from mesangial cells incubated with aggregated IgA1 from IgA nephropathy patients reduces podocyte adhesion through activation of the renin angiotensin system

Medium from mesangial cells incubated with aggregated IgA1 from IgA nephropathy patients reduces podocyte adhesion through activation of the renin angiotensin system

BACKGROUND: Podocyte injury plays an important role in glomerulosclerosis in IgA nephropathy (IgAN), and detachment from the glomerular basement membrane is the main cause of podocyte damage. In a previous study we found that medium from mesangial cells incubated with aggregated IgA1 (aIgA1) i...

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Bibliographic Details
Main Authors: C Wang, X Liu, Y Tang, H Peng, ZC Ye, J Zhang, H Tang, T Lou
Format: Article
Language:English
Published: SMW supporting association (Trägerverein Swiss Medical Weekly SMW) 2011-12-01
Series:Swiss Medical Weekly
Subjects:
adhesive
IgA nephropathy
IgA1
medium
mesangial cell
podocyte
Online Access:https://www.smw.ch/index.php/smw/article/view/1409

Internet

https://www.smw.ch/index.php/smw/article/view/1409

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