Evaluation of the Lectin Pathway in the Serum of Patients with Chronic Chagas Disease by Detection of C4 by Elisa

Evaluation of the Lectin Pathway in the Serum of Patients with Chronic Chagas Disease by Detection of C4 by Elisa

ABSTRACT Chagas disease (CD) is a chronic tropical disease caused by Trypanosoma cruzi , affecting about 8 million people in Latin America. The lectin pathway (LP) of the complement system is one of the first lines of host defense in the response against T. cruzi , and can continue to be activated i...

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Bibliographic Details
Main Authors: Renan Polachini, Lorena Bavia, Fabiana A. Andrade, Kárita C. F. Lidani, Vanessa F. Picceli, Nathalia M. D. L. Signorini, Pâmela D. Fontana, Helena M. B. S. Plácido, Iara J. M. Reason
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2022-05-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
chagas disease
complement system
complement activation
lectin pathway
mannose-binding lectin
ficolins
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442022000100100&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442022000100100&lng=en&tlng=en

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