High-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation

High-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation

Neutrophils migrate to sites of infection where they phagocytose, degranulate, and/or, in the presence of appropriate stimuli, release decondensed chromatin strands (called neutrophil extracellular traps, NETs) for trapping and possibly killing microorganisms. NET formation is characterized by marke...

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Bibliographic Details
Main Authors: Elvira Sondo, Roberta Bertelli, Emanuela Pesce, Gian Marco Ghiggeri, Nicoletta Pedemonte
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
NETosis
high-content screening
vanilloids
NETs
inhibitors
neutrophil
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00963/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00963/full

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