Characterization and Function of Glycans on the Spike Proteins of SARS-CoV-2 Variants of Concern

Characterization and Function of Glycans on the Spike Proteins of SARS-CoV-2 Variants of Concern

ABSTRACT SARS-CoV-2 variants of concern (VOCs) pose a great challenge to viral prevention and treatment owing to spike (S) protein mutations, which enhance their infectivity and capacity for immune evasion. However, whether these S protein mutations affect glycosylation patterns and thereby influenc...

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Bibliographic Details
Main Authors: Luping Zheng, Ke Wang, Minghai Chen, Fujun Qin, Chuang Yan, Xian-En Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
SARS-CoV-2
variants of concern
glycosylation pattern
receptor binding
neutralization
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03120-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.03120-22

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