Dynamic expression of desmin, α-SMA and TGF-β1 during hepatic fibrogenesis induced by selective bile duct ligation in young rats

Dynamic expression of desmin, α-SMA and TGF-β1 during hepatic fibrogenesis induced by selective bile duct ligation in young rats

We previously described a selective bile duct ligation model to elucidate the process of hepatic fibrogenesis in children with biliary atresia or intrahepatic biliary stenosis. Using this model, we identified changes in the expression of alpha smooth muscle actin (α-SMA) both in the obstructed paren...

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Bibliographic Details
Main Authors: J.O. Gonçalves, A.C.A. Tannuri, M.C.M. Coelho, I. Bendit, U. Tannuri
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2014-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Alpha smooth muscle actin
Desmin
Hepatic fibrogenesis
Selective bile duct ligation
RT-PCR
TGF-β1
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001000850&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001000850&lng=en&tlng=en

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