LncRNA HOTTIP leads to osteoarthritis progression via regulating miR-663a/ Fyn-related kinase axis

LncRNA HOTTIP leads to osteoarthritis progression via regulating miR-663a/ Fyn-related kinase axis

Abstract Background Long non-coding RNA (lncRNA) has been implicated in the progression of osteoarthritis (OA). This study was aimed to explore the role and molecular mechanism of lncRNA HOXA terminal transcriptional RNA (HOTTIP) in the development of OA. Methods The expression of HOTTIP, miR-663a a...

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Bibliographic Details
Main Authors: Xianwei He, Kun Gao, Shuaihua Lu, Rongbo Wu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Musculoskeletal Disorders
Subjects:
Osteoarthritis
Chondrocytes
FRK
miR-663a
lncRNAs HOTTIP
Online Access:https://doi.org/10.1186/s12891-020-03861-7

Internet

https://doi.org/10.1186/s12891-020-03861-7

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