Synthesis, Nanoformulations, and In Vitro Anticancer Activity of <i>N</i>-Substituted Side Chain Neocryptolepine Scaffolds

Synthesis, Nanoformulations, and In Vitro Anticancer Activity of <i>N</i>-Substituted Side Chain Neocryptolepine Scaffolds

The naturally occurring neocryptolepine (5-Methylindolo [2,3-<i>b</i>]quinoline) and its analogs exhibited prominent anticancer and antimalarial activity. However, the main problem of this class of compounds is their poor aqueous solubility, hampering their bioavailability and preventing...

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Bibliographic Details
Main Authors: Ibrahim El-Tantawy El Sayed, Sami Ullah, Omar A. Al-Hartomy, Asmaa Mohammed Hasanein, Abdullah A. S. Ahmed, Khaled A. Kahilo, Mehrez E. El-Naggar
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
nanoemulsion
anticancer activity
neocryptolepine scaffolds
Online Access:https://www.mdpi.com/1420-3049/27/3/1024

Internet

https://www.mdpi.com/1420-3049/27/3/1024

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