Causal association of type 2 diabetes with amyotrophic lateral sclerosis: new evidence from Mendelian randomization using GWAS summary statistics
Abstract Background Associations between type 2 diabetes (T2D) and amyotrophic lateral sclerosis (ALS) were discovered in observational studies in both European and East Asian populations. However, whether such associations are causal remains largely unknown. Methods We employed a two-sample Mendeli...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | BMC Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12916-019-1448-9 |