Causal association of type 2 diabetes with amyotrophic lateral sclerosis: new evidence from Mendelian randomization using GWAS summary statistics

Abstract Background Associations between type 2 diabetes (T2D) and amyotrophic lateral sclerosis (ALS) were discovered in observational studies in both European and East Asian populations. However, whether such associations are causal remains largely unknown. Methods We employed a two-sample Mendeli...

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Bibliographic Details
Main Authors: Ping Zeng, Ting Wang, Junnian Zheng, Xiang Zhou
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12916-019-1448-9