Multiscale Modeling of Macromolecular Interactions between Tau-Amylin Oligomers and Asymmetric Lipid Nanodomains That Link Alzheimer’s and Diabetic Diseases

The molecular events of protein misfolding and self-aggregation of tau and amylin are associated with the progression of Alzheimer’s and diabetes, respectively. Recent studies suggest that tau and amylin can form hetero-tau-amylin oligomers. Those hetero-oligomers are more neurotoxic than homo-tau o...

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Detalles Bibliográficos
Autores principales: Natalia Santos, Luthary Segura, Amber Lewis, Thuong Pham, Kwan H. Cheng
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2024-02-01
Colección:Molecules
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Acceso en línea:https://www.mdpi.com/1420-3049/29/3/740