PINK1/PARKIN-mediated mitophagy inhibits the interferon response and promotes viral replication during Pseudorabies virus infection

PINK1/PARKIN-mediated mitophagy inhibits the interferon response and promotes viral replication during Pseudorabies virus infection

Pseudorabies virus (PRV) poses a significant threat to the global swine industry, characterized by high morbidity and a range of sequelae in infected pigs. Mitochondria serve as a crucial platform for innate immunity, playing a pivotal role in a wide array of antiviral responses. In our recent study...

Full description

Bibliographic Details
Main Authors: Yuan Zhao, Zhenbang Zhu, Wenqiang Wang, Zhendong Zhang, Wei Wen, Xiangdong Li
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autophagy Reports
Subjects:
Pseudorabies virus
mitochondria
mitophagy
MAVS
Interferons
Online Access:https://www.tandfonline.com/doi/10.1080/27694127.2024.2422214

Internet

https://www.tandfonline.com/doi/10.1080/27694127.2024.2422214

Similar Items